Wiley Launches the Analytical Sciences Backfile Collection, AntiBase 2005 and AmicBase 2005

Apr 22, 2005


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Publisher John Wiley & Sons, Inc. has announced the launch of the Analytical Sciences Backfile Collection and AntiBase 2005 and AmicBase 2005, two new database products designed for researchers and scientists.

The Analytical Sciences Backfile Collection is the latest addition to Wiley's collection of digitized journal libraries, and the second to be launched in this year. The Cell & Developmental Biology Backfile Collection was launched in late February. The Analytical Sciences Backfile Collection is available via Wiley InterScience, Wiley's online publishing platform.

Spanning 29 years (1968-1998), the Analytical Sciences Backfile Collection contains digitized back-issue content across thirteen journal titles. The collection is intended to provide a backfile resource for core research across the discipline of analytical sciences and includes full coverage - back to inaugural issues - of such titles as Electrophoresis and Journal of Mass Spectrometry. All journal articles are presented in a fully searchable PDF format, with abstracts, bibliographic content, and literature citations all available in HTML, allowing for both internal linking to cited content located on Wiley InterScience, as well as external linking via CrossRef/DOI, PubMed, ISI Web of Science, and CAS to the content of hundreds of publishers worldwide.

Journals included in the Analytical Sciences Backfile Collection are: Biomedical Chromatography, Electroanalysis, Electrophoresis, Luminescence (formerly Journal of Bioluminescence and Chemoluminescence), Journal of Chemometrics, Journal of Mass Spectrometry (published as Biological Mass Spectrometry and Organic Mass Spectrometry until 1995), Journal of Microcolumn Separations (merged with Journal of Separation Science in 1999), Journal of Raman Spectroscopy, Journal of Separation Science (formerly Journal of High Resolution Chromatography), Magnetic Resonance in Chemistry (formerly Organic Magnetic Resonance), Mass Spectrometry Reviews, Rapid Communications in Mass Spectrometry, and X-Ray Spectrometry.

Wiley has also announced the launch of AntiBase 2005 and AmicBase 2005, two new database products designed for researchers and scientists in organic chemistry, biochemistry, biotechnology, and pharmaceuticals. AntiBase 2005 is a database of 31,022 natural compounds from microorganisms and higher fungi. The data in AntiBase 2005 have been collected from the primary and secondary literature and then carefully checked and validated. Included in the database: descriptive data (molecular formula and mass, elemental composition, CAS registry number); physico-chemical data (melting point, optical rotation); spectroscopic data (UV, 13C-NMR, IR and mass spectra); biological data (pharmacological activity, toxicity); information on origin and isolation; and a summary of literature sources.

For those compounds where no measured spectra are available, the 2005 edition of AntiBase utilizes predicted 13C-NMR spectra produced by SpecInfo, the spectrum prediction program. Calculated high resolution molecular masses are also included in this new update. Other features included in AntiBase 2005: structure and substructure search capabilities; drawing tools ISIS/Draw and Chemdraw to draw structure or substructure queries; physical and biological data search; and a feature search that enables the natural product chemist to identify a given compound if it has already been isolated and stored in the database. Edited by Hartmut Laatsch of the University of Göttingen, Germany, AntiBase 2005 updates previous editions of the database released in 2002 and 2003, and will be updated annually. AntiBase 2005 is available in the following formats: ISIS/Base and ChemFinder.

AmicBase 2005 contains information about the antimicrobial and toxicological properties of pharmaceutical drugs and natural compounds produced through microorganisms and higher plants. Compound groups included in the database are approved antibiotic drugs available in United States, Japan and Europe and encompass antiseptics, disinfectants and preservatives used in food, cosmetics and in the pharmaceutical industry. The database contains 160,149 data records of 7,474 compounds and includes: descriptive data (molecular formula and mass, CAS number, EINECS, 2D and 3D structures); inhibitory data (MIC and others) including a brief description of test method and references; and toxicology data (LD50), which also include short references.

AmicBase 2005 features functionalities that include: structure and substructure searches; drawing tools to draw structure or substructure queries; searches by drug activity and microbial species; and displays that detail the antimicrobial spectra of drugs and calculates therapeutic indices from literature data. Searches can also be combined with compound structures or toxicological data.

AmicBase 2005 Drugs--a component of the larger AmicBase 2005 database--is a stand-alone database that contains information about the antimicrobial and toxicological properties of pharmaceutical drugs, and features detailed activity spectra of antibacterial and antifungal drugs marketed in Unites States, Japan, and Europe. The database contains 57, 718 data records from 608 compounds and includes: descriptive data (molecular formula and mass, CAS number, EINECS, 2D and 3D structures); inhibitory data (MIC and others) with a brief description of test methods and references; and toxicology data (LD50), which also include short references.

AmicBase 2005 Drugs features a tool that allows users to get information quickly about the antimicrobial activity of drugs being used to treat human infectious diseases. Other features include: structure and substructure searches; drawing tools to draw structure and substructure queries; searches by drug activity and microbial species; and displays that detail the antimicrobial spectra of drugs and calculates therapeutic indices from literature data. As with the larger AmicBase database, searches can also be combined with compound structures or toxicological data.

AmicBase 2005 Plants--also a stand-alone component of AmicBase 2005--is a database that collects information about the antimicrobial and toxicological properties of natural compounds produced by higher plants, and contains data on compounds produced from preservatives, fatty acids, and perfumery chemicals. AmicBase 2005 Plants contains 77,149 data records from 4,986 compounds and also includes: descriptive data (molecular formula and mass, CAS number, EINECS, 2D and 3D structures); inhibitory data (MIC and others) with brief descriptions of test methods and references; and toxicology data (LD50) also with short references. The search features for AmicBase 2005 Plants are the same as those for AmicBase 2005 Drugs and the larger AmicBase 2005 database. Alexander Pauli is the editor of all three AmicBase databases.
(www.interscience.wiley.com; www.wiley.com)